Over-the-counter Head Lice Treatments not Always Enough - Mayo Clinic News Network (2025)

  • Health & Wellness

    By

    Shawn Bishop

Over-the-counter Head Lice Treatments not Always Enough

May 27, 2011

Dear Mayo Clinic:

I hear head lice are making a comeback and that over-the-counter treatments don't work. What's the best way to treat head lice?

Answer:

Head lice seem to be more prominent now than in the past. The reason why is difficult to determine. Perhaps it's simply the natural life cycle of this infestation, or that the public is more aware of head lice. Over-the-counter treatments for head lice can often be effective but don't work in all cases. If head lice persist despite treatment at home, then it's time to see a doctor.

Head liceare tiny, wingless, parasitic insects that live and feed on blood from a person's scalp. They cause a lot of fear, anxiety and concern. But, fortunately, although a nuisance, head lice don't carry any dangerous transmissible diseases.

Head lice can spread easily. They may migrate from one person to another through direct contact or they can be passed through shared items, such as combs, hair brushes and towels. Head lice tend to stay within about an inch of the scalp, anchoring onto a hair shaft. If you suspect that you or a family member has head lice, the best places to look are behind the ears and along the back of the neck, near the scalp. Lice are very small, about the size of a strawberry seed. Their eggs (nits) resemble tiny pussy willow buds. Nits can be mistaken for dandruff, but they can't be easily brushed out of hair.

Because head lice often move rapidly through groups who have close contact, such as schoolchildren, prompt treatment is important to minimize spread. Many preschools, day care centers and elementary schools prohibit children with head lice from attending until they've been effectively treated.

Plenty of over-the-counter treatments for head lice are available. The most common are shampoos containing medications such as pyrethrin or permethrin, which kill the lice. In several regions of the country, however, some lice strains have become resistant to these medications. If you live in one of these areas, or if you try over-the-counter treatments and they don't work, make an appointment with your primary care doctor or a dermatologist to seek prescription treatment. Prescription creams or shampoos may help eliminate head lice when over-the-counter treatments aren't effective.

To catch the full life cycle of head lice, treatment should be used more than once. Using only one treatment will not affect head lice that are still in egg stage. To be most effective, treatment should be repeated seven or eight days after the first application.

If you don't want to use medications that kill head lice, a fine-toothed comb or nit comb can physically remove the lice from wet hair. This method, to be effective, needs to be repeated every three to four days for at least two weeks. However, removing all the lice and nits this way can be difficult.

Home remedies such as putting mayonnaise, oils or petroleum jelly on the scalp to suffocate head lice are rarely effective. Some people try to kill head lice with heat, using an extra-hot hair dryer. Putting kerosene on the hair is also sometimes used as a way to kill lice. These techniques can lead to severe burns. Do not use them.

If one person in your household has head lice, everyone who lives in your home or has prolonged exposure within the home — such as babysitters or overnight guests — should be treated. If school-age or preschool children are affected, notify their school or day care center.

Thoroughly wash all the materials and equipment that the person affected with head lice regularly uses, including combs, towels, washcloths, bedding and sheets. Vacuuming household furniture is also a good idea to help eliminate head lice from your home and prevent another infestation.

— Dawn Davis, M.D., Dermatology, Mayo Clinic, Rochester, Minn.

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FAQs

Over-the-counter Head Lice Treatments not Always Enough - Mayo Clinic News Network? ›

Some strains of lice can be resistant to over-the-counter treatments. If head lice persist despite treatment at home, contact your health care provider to discuss prescription medication alternatives. Head lice are tiny, wingless, parasitic insects that live and feed on blood from a person's scalp.

What to do when over-the-counter lice treatment doesn't work? ›

The doctor may order a prescription lice medicine if the over the counter medicine does not work. A prescription medicine might be needed for treating lice in a very young child. These medicines have chemicals that are different than the over-the-counter medicines.

Why isn't lice treatment working? ›

If you tried an OTC head lice treatment that didn't work and you are certain that your child didn't get reinfested, seek professional help. It's possible that you are dealing with head lice that are resistant to the active ingredient in your treatment product.

How effective is OTC lice treatment? ›

Various OTC and prescription shampoos and lotions are effective for killing lice, but you'll need to choose the formula that's right for you or your family member. Some are not recommended for children below a certain age. The first treatment may not kill all the lice and eggs (called nits).

What is the absolute best lice treatment? ›

Best Overall

Malathion Ovide Lotion is a prescription-strength lotion that comes highly recommended by experts for treating lice.

How to get rid of lice when nothing else works? ›

A dermatologist can also recommend an effective treatment for your child. This may be one of the prescription treatments. Sometimes, simply combing your child's hair to remove the lice and nits (eggs) can be effective. While time-consuming, studies show that combing injures the lice, so they rarely survive.

How do you treat stubborn head lice? ›

Using insecticide products

If you use a lotion, apply the product to dry hair. For shampoo products, wet the hair, but use as little water as possible. Head lice live in the hair and go to the scalp to feed. Therefore, head lice products must be applied to all parts of the hair.

Do dead lice fall out of hair? ›

The female louse secretes this glue-like substance when she lays her eggs to protect them until they hatch. The glue hardens upon secretion and does not dissipate when a nit dies. For that reason, dead lice remain cemented onto the hair shaft until you manually or chemically remove them or the hair grows out.

Why do I still have lice after 3 treatments? ›

There are two reasons for a recurrent lice infestation: The lice treatment you used didn't work. You or someone in your family came in contact with lice again.

What kills head lice instantly? ›

What kills head lice instantly? No methods have been found to instantly kill lice, though tea tree and lavender oil combinations in carrier oils have proven to be effective and time-efficient.

What is the best over the counter medicine for lice? ›

Permethrin lotion 1% is approved by the FDA for the treatment of head lice. Permethrin is safe and effective when used as directed. Permethrin kills live lice but not unhatched eggs. Permethrin may continue to kill newly hatched lice for several days after treatment.

How long do lice live on a mattress? ›

Without a host, lice can survive on your mattress for up to 48 hours, but during this time, they can continue to lay eggs and multiply, which can lead to a more severe infestation. It's essential to take action to get rid of lice and prevent their multiplication.

How long can lice live on a hairbrush? ›

The CDC also advises against sharing hairbrushes. Adult head lice can survive for 2 days and nits for around 1 week on a hairbrush. Soaking combs or hairbrushes in hot water of at least 130°F (54.4°C) for 5–10 minutes will kill any lice and nits.

Is Nix or Rid better? ›

The medicine in Nix® is recognized as the most effective over-the-counter treatment for killing lice and their eggs according to the Academy of Pediatrics. That's why parents turn to Nix®, the #1 Pediatrician and Pharmacist recommended brand…

Does Vamoose really work for lice? ›

In the end it worked, and this stuff is far more effective than the Pyrethrin based products from years ago that it replaces . It seems lice have evolved past that. In the past we even tried Listerine on the hair because Nix and those like it were so ineffective. This is much better.

What treats super lice? ›

Nix® Ultra is highly effective for killing lice, superlice and their eggs.

How do you get rid of treatment resistant lice? ›

The Cetaphil method has been proven to eliminate these resistant lice. Cetaphil skin cleanser is a gentle over the counter skin cleanser. A study from 2004 shows a 96 to 97% success rate at eliminating these mutant lice. This treatment works by suffocating the lice.

What if I have lice treatment but no lice? ›

What to do if you've found nits but no lice after treatment. If you're still finding nits but no lice after you've undergone treatment, continue combing your hair with a nit comb every 2 to 3 days , according to the CDC. Additionally, for some medications, re-treatment is recommended routinely after the first treatment ...

Why am I still finding lice after treatment? ›

If your child or someone else in your family still has head lice after a few weeks, it means that the treatments did not work or the person got lice again. Make an appointment to see a dermatologist for help getting rid of the head lice.

What happens if you don t get all the nits out after lice treatment? ›

Any nits that were left behind after the first treatment will be taken care of in the second and third treatments. If you find a lot of nits after the first treatment, then do the recommended quick comb-outs with the nit comb and KaPOW! ™ Lice Defense Spray to help the comb glide through the hair.

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